Article
COVID-19-specific metabolic imprint yields insights into multiorgan system perturbations.
European journal of immunology - 1 Mar 2022
Cornillet Martin, Strunz Benedikt, Rooyackers Olav, Ponzetta Andrea, Chen Puran, Muvva Jagadeeswara Rao, Akber Mira, Buggert Marcus, Chambers Benedict J, Dzidic Majda, Filipovic Iva, Gorin Jean-Baptiste, Gredmark-Russ Sara, Hertwig Laura, Klingström Jonas, Kokkinou Efthymia, Kvedaraite Egle, Lourda Magda, Mjösberg Jenny, Maucourant Christopher, Norrby-Teglund Anna, Parrot Tiphaine, Perez-Potti André, Rivera-Ballesteros Olga, Sandberg Johan K, Sandberg John Tyler, Sekine Takuya, Svensson Mattias, Varnaite Renata, Eriksson Lars I, Aleman Soo, Strålin Kristoffer, Ljunggren Hans-Gustaf, Björkström Niklas K
Abstract excerpt
Corona disease 2019 (COVID-19) affects multiple organ systems. Recent studies have indicated perturbations in the circulating metabolome linked to COVID-19 severity. However, several questions pertain with respect to the metabolome in COVID-19. We performed an in-depth assessment of 1129 unique metabolites in 27 hospitalized COVID-19 patients and integrated results with large-scale proteomic and immunology data...
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