Article

A highly resolved integrated single-cell atlas of HPV-negative head and neck cancer

2025-03-04

Abstract excerpt

Head and Neck Squamous Cell Carcinomas (HNSCC) are the seventh most prevalent form of cancer and are associated with human papilloma virus infection (HPV-positive) or with tobacco and alcohol use (HPV-negative). HPV-negative HNSCCs have a high recurrence rate, and individual patients’ responses to treatment vary greatly due to the high level of cellular heterogeneity of the tumor and its microenvironment. Here, we...

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Literature Corpus work: 4c45ef4f-b314-504c-bf5c-70d4b1760552
DOI: 10.1101/2025.03.02.640812

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