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Investigating immune and non-immune cell interactions in head and neck tumors by single-cell RNA sequencing

17 Dec 2021

Abstract excerpt

Abstract Head and neck squamous cell carcinoma (HNSCC) is characterized by complex relations between stromal, epithelial, and immune cells within the tumor microenvironment (TME). To enable the development of more efficacious therapies, we aim to study the heterogeneity, signatures of unique cell populations, and cell-cell interactions of non-immune and immune cell populations in 6 human papillomavirus (HPV) +...

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PMID: 34921143
DOI: 10.1038/s41467-021-27619-4

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