Back to search

Article

Leonurine exerts anti-inflammatory effects in LPS-induced endometritis by modulating the mouse JAK-STAT/PI3K-Akt/PPAR signalling pathway based on transcriptomic analysis

2024-02-08

Abstract excerpt

Endometritis is a common disease in postpartum cows characterized by delayed uterine recovery due to inflammation of the endometrium. Although antibiotics and hormones are commonly used for treatment, they have their limitations. One potential alternative is the use of motherwort extract, specifically leonurine, which has been found to possess anti-inflammatory properties. However, the exact molecular mechanism of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4c2e305b-393e-58c0-936e-955cb9c83eaf
DOI
10.21203/rs.3.rs-3917336/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Leonurine exerts anti-inflammatory effects in LPS-induced endometritis by modulating the mouse JAK-STAT/PI3K-Akt/PPAR signalling pathway based on transcriptomic analysisDOI 10.21203/rs.3.rs-3917336/v1
Leonurine Exerts Anti-Inflammatory Effects in Lipopolysaccharide (LPS)-Induced Endometritis by Modulating Mouse JAK-STAT/PI3K-Akt/PPAR Signaling PathwaysSemantic proximity
Alterations in Signaling Pathways and Therapeutic Strategies of Traditional Chinese Medicine in Granulomatous Lobular MastitisSemantic proximity
Modified Guishen Pill Ameliorates Polycystic Ovary Syndrome in Rats Through Anti-inflammation and Modulating Gut MicrobiotaSemantic proximity
Hemin Inhibits the Activation of STING in Macrophages by Inducing HO-1, Promoting Endometriosis DevelopmentSemantic proximity
Development of novel treatment strategies for inflammatory diseases—similarities and divergence between glucocorticoids and GILZSemantic proximity
Celastrol induces premature ovarian insufficiency by inducing apoptosis in granulosa cellsSemantic proximity
PrPC Promotes Endometriosis Progression by Reprogramming Cholesterol Metabolism and Estrogen Biosynthesis of Endometrial Stromal Cells through PPARα PathwaySemantic proximity
Selenium and Selenoproteins in Gut Inflammation—A ReviewSemantic proximity
Peroxisome Proliferator-Activated Receptor-Targeted Therapies: Challenges upon Infectious DiseasesSemantic proximity
Jianwei Shoutai Pills alleviates miscarriage by modulating gut microbial production of BAs and NLRP3-inflammasome at the maternal-fetal interface of ratsSemantic proximity
Human placental mesenchymal stem cells ameliorates premature ovarian insufficiency via modulating gut microbiota and suppressing the inflammation in ratsSemantic proximity
Indole-3-carbinol Inhibits Lipopolysaccharides-induced Small Intestinal Inflammation and Metabolic Disorder by Improving Glycerophospholipids Metabolism in RabbitsSemantic proximity
Select a neighboring publication to make it the new centre.