Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PrPC Promotes Endometriosis Progression by Reprogramming Cholesterol Metabolism and Estrogen Biosynthesis of Endometrial Stromal Cells through PPARα Pathway

1 Jan 2022

Abstract excerpt

Endometriosis (EMs) is characterized as an estrogen-dependent disease. Whereas, the underlying mechanism for activated estrogen biosynthesis in EMs lesions is largely unknown. We analyzed cholesterol metabolism and estrogen biosynthesis condition of EMs lesions by biological information analysis of GEO datasets, and further verified both in vitro and in vivo by constructing EMs models with uterus fragments from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometriosis Research and Treatment
Share to Reproductive System and Pregnancy
Share to Uterine Myomas and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35280685
DOI: 10.7150/ijbs.68015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PrPC Promotes Endometriosis Progression by Reprogramming Cholesterol Metabolism and Estrogen Biosynthesis of Endometrial Stromal Cells through PPARα PathwayPMID 35280685Read ↗

Endometrial Hyperplasia Risk Is Increased by High-Fat Diet Via Estrogen-Driven Stromal Fibroblast Reprogramming Toward a Pro-Fibrotic StateSemantic proximity Read ↗

Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune responseSemantic proximity Read ↗

Genomic Function of Estrogen Receptor β in EndometriosisSemantic proximity Read ↗

Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune responseSemantic proximity Read ↗

Single-cell analysis identifies distinct macrophage phenotypes associated with pro-disease and pro-resolving functions in the endometriotic nicheSemantic proximity Read ↗

Single-cell analysis identifies distinct macrophage phenotypes associated with prodisease and proresolving functions in the endometriotic niche.Semantic proximity Read ↗

Endometriosis: Perspective, lights, and shadows of etiology.Semantic proximity Read ↗

A PubMed-wide study of endometriosis.Semantic proximity Read ↗

Hemin Inhibits the Activation of STING in Macrophages by Inducing HO-1, Promoting Endometriosis DevelopmentSemantic proximity Read ↗

Monogenic Contributions to Familial Endometriosis: A Scoping Review.Semantic proximity Read ↗

Epithelial Cell Line Derived from Endometriotic Lesion Mimics Macrophage Nervous Mechanism of Pain Generation on Proteome and Metabolome Levels.Semantic proximity Read ↗

Immunological Dysregulation in Endometriosis Potentially Linked to Anomalies in NCOA4-Mediated Iron Autophagy PathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.