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Residual Partial Least Squares Learning: Brain Cortical Thickness Simultaneously Predicts Eight Non-pairwise-correlated Behavioural and Disease Outcomes in Alzheimer's Disease

2024-03-13

Abstract excerpt

Alzheimer's Disease (AD) is the leading cause of dementia, affecting brain structure, function, cognition, and behaviour. While previous studies have linked brain regions to univariate outcomes (e.g., disease status), the relationship between brain-wide changes and multiple disease and behavioural outcomes of AD is still not well understood. Here, we propose Residual Partial Least Squares (re-PLS) Learning, an exp...

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Literature Corpus work: 4c0ea8b3-f66d-5896-98c1-4a8d5944fb41
DOI: 10.1101/2024.03.11.584383

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