Article

Ollivier Ricci Curvature as a Geometric Biomarker for Biomedical Networks: From Ontology to Comorbidity Aging Trajectories

2026-03-16

Abstract excerpt

Network geometry offers a principled lens for understanding the structure of biomedical knowledge. We apply exact Ollivier-Ricci curvature (ORC) -- a discrete analogue of Riemannian curvature computed via optimal transport -- to medical ontologies, disease comorbidity networks, biological interaction networks, and brain functional connectivity graphs. Three main results emerge. First, within a single database (the...

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Literature Corpus work: 4be7049a-81cc-5d15-a9b8-a8ada7c41846
DOI: 10.64898/2026.03.14.26348393

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