Article

Severe traumatic brain injury temporally affects cerebral blood flow, endothelial cell phenotype, and cilia

2024-11-21

Abstract excerpt

<h4>Background</h4> Previous clinical work suggested that altered cerebral blood flow (CBF) in severe traumatic brain injury (sTBI) correlates with poor executive function and clinical outcome. However, the molecular consequences of altered CBF on endothelial cells (ECs) and their blood flow-sensor organelle called cilia are not known. <h4>Methods</h4> We performed laser speckle contrast imaging, single cell iso...

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Literature Corpus work: 4be18596-00fe-536c-85ab-1a8d01df8423
DOI: 10.1101/2024.11.19.623875

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