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Targeting the ITGA3B1 Complex with A Novel Antibody-Drug Conjugate for Metastatic Bladder Cancer

2025-04-07

Abstract excerpt

Advances in antibody (Ab) phage display technologies have enabled the development of targeted therapies with enhanced precision and clinical efficacy. Here, we report a phenotypic screening strategy combining target-unbiased live-cell biopanning with in situ chemical crosslinking and mass spectrometry to identify internalizing antibodies and their cognate antigens—key features for effective antibody-drug conjugate...

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Literature Corpus work
4b71db79-28a8-5b7c-a142-e15a3ec6c961
DOI
10.1101/2025.04.06.647354
Open publication

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Targeting the ITGA3B1 Complex with A Novel Antibody-Drug Conjugate for Metastatic Bladder CancerDOI 10.1101/2025.04.06.647354
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