Article

Genetic determinants that permit growth without the core septin Cdc12 in <i>Cryptococcus neoformans</i>

2025-12-17

Abstract excerpt

<h4>ABSTRACT</h4> Septins are conserved cytoskeletal GTPases that regulate morphogenesis, cytokinesis, and cell-surface organization in fungi. In most model and pathogenic yeasts, including Saccharomyces cerevisiae and Candida albicans , core septin subunits such as Cdc3 and Cdc12 are essential and their loss results in lethal cytokinetic defects. In Cryptococcus neoformans , by contrast, deletion of CDC12 yi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4b298ac9-aed5-50f4-a12c-7722237956a8
DOI: 10.64898/2025.12.17.694962

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic determinants that permit growth without the core septin Cdc12 in <i>Cryptococcus neoformans</i>DOI 10.64898/2025.12.17.694962Read

Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformansSemantic proximity Read

Cell Wall Integrity Pathway Involved in Morphogenesis, Virulence and Antifungal Susceptibility in Cryptococcus neoformansSemantic proximity Read

Two CDC42 paralogues modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditionsSemantic proximity Read

The enigmatic role of fungal annexins: the case of <i>Cryptococcus neoformans</i>Semantic proximity Read

A gene duplication of a septin provides a developmentally-regulated filament length control mechanismSemantic proximity Read

<i>Cryptococcus neoformans</i> Slu7 ensures nuclear positioning during mitotic progression through RNA splicingSemantic proximity Read

Calcineurin controls the cytokinesis machinery during thermal stress in <i>Cryptococcus deneoformans</i>Semantic proximity Read

A fungal arrestin protein contributes to cell cycle progression and pathogenesisSemantic proximity Read

Deletion of core septin gene <i>aspB</i> in <i>Aspergillus fumigatus</i> results in fungicidal activity of caspofunginSemantic proximity Read

Phenotypic landscape of a fungal meningitis pathogen reveals its unique biologySemantic proximity Read

The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulenceSemantic proximity Read

Transcription Factors and Intracellular Proteins Orchestrate Phenotypic Adaptation in Cryptococcus neoformans for Survival and Human InfectionsSemantic proximity Read