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Article

Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans

25 Nov 2009

Abstract excerpt

Septins are conserved, cytoskeletal GTPases that contribute to cytokinesis, exocytosis, cell surface organization and vesicle fusion by mechanisms that are poorly understood. Roles of septins in morphogenesis and virulence of a human pathogen and basidiomycetous yeast Cryptococcus neoformans were investigated. In contrast to a well-established paradigm in S. cerevisiae, Cdc3 and Cdc12 septin homologues are...

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PMID: 19943902
DOI: 10.1111/j.1365-2958.2009.06983.x

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Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformansPMID 19943902Read ↗

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A Candida albicans temperature-sensitive cdc12-6 mutant identifies roles for septins in selection of sites of germ tube formation and hyphal morphogenesis.Semantic proximity Read ↗

An Ustilago maydis septin is required for filamentous growth in culture and for full symptom development on maize.Semantic proximity Read ↗

A septin from the filamentous fungus A. nidulans induces atypical pseudohyphae in the budding yeast S. cerevisiae.Semantic proximity Read ↗

Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis.Semantic proximity Read ↗

A gene duplication of a septin provides a developmentally-regulated filament length control mechanismSemantic proximity Read ↗

Function of Cryptococcus neoformans KAR7 (SEC66) in karyogamy during unisexual and opposite-sex mating.Semantic proximity Read ↗

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