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Use of Axenic Culture Tools to Study Coxiella burnetii

18 May 2018

Abstract excerpt

Coxiella burnetii is a highly infectious obligate intracellular bacterium and the etiological agent of the zoonosis Query (Q) fever. This Gram-negative gamma-proteobacterium has adapted to replicate within a specialized compartment in mammalian phagocytic cells, known as the Coxiella-containing vacuole (CCV). Knowledge of critical characteristics of the CCV microenvironment (e.g., luminal pH), analysis of the C....

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PMID: 29927105
DOI: 10.1002/cpmc.52

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