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Coxiella burnetii: A Pathogenic Intracellular Acidophile

13 Nov 2018

Abstract excerpt

Coxiella burnetii is an obligate intracellular pathogen that causes acute and chronic Q fever. C. burnetii grows within a eukaryotic host cell in a vacuole highly similar to a phagolysosome. Found worldwide, this environmentally stable pathogen is maintained in nature via chronic infection of ruminants. Aerosol-mediated infection of humans results in infection and usurpation of alveolar macrophages through...

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PMID: 30422108
DOI: 10.1099/mic.0.000707

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