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Precision cut intestinal slices, a novel model of acute food allergic reactions

2022-09-22

Abstract excerpt

<h4>Background: </h4> Food allergy affects up to 8% of the pediatric population. Despite ongoing efforts, treatment options remain limited. Novel models of food allergy are needed to study response patterns downstream of IgE-crosslinking and evaluate drugs modifying acute events. Here, we report a novel human ex vivo model that displays acute, allergen-specific, IgE-mediated smooth muscle contractions using preci...

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Literature Corpus work
4ac6b580-30b1-5942-9940-8e4b0a55cff8
DOI
10.22541/au.166382124.43210924/v1
Open publication

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Precision cut intestinal slices, a novel model of acute food allergic reactionsDOI 10.22541/au.166382124.43210924/v1
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