Article

Characterization of a cell death mechanism in a mouse model of multiple sulfatase deficiency : role of mitochondrial autophagy

2011-01-01

Abstract excerpt

Mitochondria are organelles recognized as central players in cell death. Dysfunctional mitochondria are a well-known hallmark of disease since the accumulation of aberrant mitochondria can alter cell homeostasis thus resulting in tissue degeneration. Lysosomal storage disorders (LSDs) are a group of genetic diseases characterized by the accumulation of un-degraded material inside lysosomes that leads to autophagic...

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Literature Corpus work: 4aae875f-18e6-5123-b18b-462f3e31d076
DOI: 10.21954/ou.ro.0000f1a5

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