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Single intranasal immunization with attenuated Wuhan-like SARS-CoV-2 provides highly effective cross-protection against Delta and Omicron VOCs

2023-10-09

Abstract excerpt

<title>Abstract</title> <p>Despite the end of the COVID-19 pandemic, the problem of vaccine prevention of this disease appears highly relevant. The emergence and widespread distribution of the Omicron SARS-CoV-2 variant of concern (VOC) and its sublineages has dramatically reduced the efficacy of vaccination with licensed vaccines. The possible approach to solving this problem is to develop a nasal live attenuate...

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Identifiers and source

Literature Corpus work
29ca0825-a82e-5a4c-ae64-c18a02056e27
DOI
10.21203/rs.3.rs-3279049/v1
Open publication

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Single intranasal immunization with attenuated Wuhan-like SARS-CoV-2 provides highly effective cross-protection against Delta and Omicron VOCsDOI 10.21203/rs.3.rs-3279049/v1
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