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Pix2Path: Integrating Spatial Transcriptomics and Digital Pathology with Deep Learning to Score Pathological Risk and Link Gene Expression to Disease Mechanisms

2024-08-19

Abstract excerpt

Spatial transcriptomics (ST) provides high-resolution mapping of gene expression within tissues, and integrating ST with digital pathology can offer unprecedented insights into the molecular mechanisms underlying various diseases. However, existing methods primarily focus on aligning these two distinct datasets, often neglecting the causal connections between spatial gene activity and pathological phenotype. We in...

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Literature Corpus work
49fc9eeb-c469-58f6-8fe0-ef3c329c4b5f
DOI
10.1101/2024.08.18.608468
Open publication

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Pix2Path: Integrating Spatial Transcriptomics and Digital Pathology with Deep Learning to Score Pathological Risk and Link Gene Expression to Disease MechanismsDOI 10.1101/2024.08.18.608468
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