Article

The hunt for ancient prions: Archaeal prion-like domains form amyloids and substitute for yeast prion domains

2020-07-21

Abstract excerpt

Prions are proteins capable of acquiring an alternate conformation that can then induce additional copies to adopt this same alternate conformation. Although initially discovered in relation to mammalian disease, subsequent studies have revealed the presence of prions in Bacteria and Viruses, suggesting an ancient evolutionary origin. Here we explore whether prions exist in Archaea - the last domain of life left u...

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Literature Corpus work: 49f0132a-333c-50d7-8ffd-f541d78193d7
DOI: 10.1101/2020.07.20.212902

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