Article

Predicting the Functional Impact of KCNQ1 Variants with Artificial Neural Networks

2021-12-09

Abstract excerpt

Recent advances in experimental and computational protein structure determination have provided access to high-quality structures for most human proteins and mutants thereof. However, linking changes in structure in protein mutants to functional impact remains an active area of method development. If successful, such methods can ultimately assist physicians in taking appropriate treatment decisions. This work pres...

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Literature Corpus work: 49dac493-828d-5d75-b52e-2985742d09d5
DOI: 10.1101/2021.12.06.471347

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