Article
Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer's disease.
PLoS genetics - 1 Jul 2017
Lu Qiongshi, Powles Ryan L, Abdallah Sarah, Ou Derek, Wang Qian, Hu Yiming, Lu Yisi, Liu Wei, Li Boyang, Mukherjee Shubhabrata, Crane Paul K, Zhao Hongyu
Abstract excerpt
Continuing efforts from large international consortia have made genome-wide epigenomic and transcriptomic annotation data publicly available for a variety of cell and tissue types. However, synthesis of these datasets into effective summary metrics to characterize the functional non-coding genome remains a challenge. Here, we present GenoSkyline-Plus, an extension of our previous work through integration of an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.