Article

Fc-independent neutralization of SARS-CoV-2 by recombinant human monoclonal antibodies

2021-05-15

Abstract excerpt

The use of passively-administered neutralizing antibodies is a promising approach for the prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may involve immune system recruitment through Fc-dependent activation of effector cells and the complement system. However, the role of Fc-mediated functions in the efficacious in vivo neutralization of SARS-CoV-2 is not yet clear. Delineating the...

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Literature Corpus work: 497dc9fa-ab54-5832-a36a-9612f8f55c5f
DOI: 10.1101/2021.05.15.443978

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