Article

Research progress in Fc-effector functions against SARS-CoV-2

2024-04-27

Abstract excerpt

SARS-CoV-2 pandemic has caused more than 676 million cases in the global human population with approximately 7 million deaths and vaccination has been proved as the most effective countermeasure in reducing clinical complications and deaths of SARS-CoV-2 infection. However, the protective elements induced by vaccine are still not completely understood. Various antibodies with multiple protective mechanisms can be...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: aabdaa6e-07d1-5852-8f04-08e7f464157e
DOI: 10.22541/au.171418771.10286841/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Research progress in Fc-effector functions against SARS-CoV-2DOI 10.22541/au.171418771.10286841/v1Read

Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infectionSemantic proximity Read

Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2Semantic proximity Read

The recombinant subunit vaccine RBD-Fc, consisting of SARS-CoV-2 RBD and human IgG Fc as an immunopotentiator, elicits robust neutralizing antibody responses against SARS-CoV-2 infectionSemantic proximity Read

Fc-independent neutralization of SARS-CoV-2 by recombinant human monoclonal antibodiesSemantic proximity Read

A SARS-CoV-2 variant of concern triggers Fc effector function with increased cross-reactivitySemantic proximity Read

Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccinationSemantic proximity Read

Fc-engineered antibody therapeutics with improved efficacy against COVID-19Semantic proximity Read

Waning and boosting of antibody Fc-effector functions upon SARS-CoV-2 vaccinationSemantic proximity Read

Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccinationSemantic proximity Read

mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concernSemantic proximity Read

Waning and boosting of functional humoral immunity to SARS-CoV-2Semantic proximity Read

Characteristics and functions of infection-enhancing antibodies to the N-terminal domain of SARS-CoV-2Semantic proximity Read