Article

ENTPD1 (CD39) and NT5E (CD73) expression in human Glioblastoma: an in silico analysis

2022-05-12

Abstract excerpt

Glioblastoma is the most common primary brain tumor in adults. It has a poor prognosis and the available lines of treatment have barely improved patient survival over the past decade. ENTPD1 and NT5E are genes that encode the cell surface enzymes CD39 and CD73, respectively. Both act in a purinergic extracellular pathway, hydrolyzing ATP into adenosine, promoting tumor immunosuppression, neovascularization and inv...

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Literature Corpus work: 492f9932-a473-574b-aa20-0a36e602b38c
DOI: 10.21203/rs.3.rs-1636293/v1

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