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Article

Characterization of purinergic signaling in tumor-infiltrating lymphocytes from lower- and high-grade gliomas.

Purinergic signalling - 1 Feb 2024

Scholl Juliete Nathali, Weber Augusto Ferreira, Dias Camila Kehl, Lima Vinícius Pierdoná, Grun Lucas Kich, Zambonin Diego, Anzolin Eduardo, Dos Santos Dias Wanderson Willian, Kus Willian Pegoraro, Barbé-Tuana Florencia, Battastini Ana Maria Oliveira, Worm Paulo Valdeci, Figueiró Fabrício

Abstract excerpt

Malignant gliomas are highly heterogeneous glia-derived tumors that present an aggressive and invasive nature, with a dismal prognosis. The multi-dimensional interactions between glioma cells and other tumor microenvironment (TME) non-tumoral components constitute a challenge to finding successful treatment strategies. Several molecules, such as extracellular purines, participate in signaling events and support...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36964277
DOI: 10.1007/s11302-023-09931-4
PMCID: PMC10828327

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