Article

Metachronous esophageal squamous cell carcinoma and hepatocellular carcinoma in the absence of common hereditary syndromes: an unusual case report and literature review

2025-12-01

Abstract excerpt

<title>Abstract</title> <p>Introduction and Importance Metachronous primary malignancies involving esophageal squamous cell carcinoma (ESCC) and hepatocellular carcinoma (HCC) are rare. Although shared risk factors such as alcohol and tobacco use are recognized, the development of these cancers in a non-cirrhotic liver and in the absence of common hereditary syndromes poses considerable diagnostic and therapeutic...

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Literature Corpus work: 48fcaa23-411f-570e-90a5-dd0e48f593e9
DOI: 10.21203/rs.3.rs-8098409/v1

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