Article
Younger age of onset and multiple primary lesions associated with esophageal squamous cell carcinoma cases with a positive family history of the cancer suggests genetic predisposition.
Chinese medical journal - 1 Jan 2014
Jia Nan, Wen Xiaoduo, Zhang Nan, Yang Yi, Zhang Liwei, Wang Xiaoling, Wang Na, Wen Denggui
Abstract excerpt
BACKGROUND: Previous epidemiological studies have consistently found a positive family history of esophageal cancer is associated with a significantly increased risk of the cancer. However, whether the elevated risk could be attributed to common household exposure or inherited susceptibility is uncertain. This study aimed to highlight the effect of genetic predisposition by noting the significant differences in...
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