Article
Risk of metachronous squamous cell carcinoma in the upper aerodigestive tract of Japanese alcoholic men with esophageal squamous cell carcinoma: a long-term endoscopic follow-up study.
Cancer science - 1 Jun 2008
Yokoyama Akira, Omori Tai, Yokoyama Tetsuji, Sato Yasuo, Kawakubo Hirofumi, Maruyama Katsuya
Abstract excerpt
East Asian case-control studies have shown a strong relationship between alcohol consumption combined with inactive heterozygous aldehyde dehydrogenase-2 (ALDH2*1/*2) and the development of squamous cell carcinoma (SCC), especially multiple SCC, of the upper aerodigestive tract (UADT). This study aimed to identify determinants of the development of metachronous SCC in the UADT in alcoholics with esophageal SCC....
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