Article

Integration of bioinformatics and machine learning strategies identifies APM-related gene signatures to predict clinical outcomes and therapeutic responses for breast cancer patients

2022-12-09

Abstract excerpt

<title>Abstract</title> <p>Background: Tumor antigenicity and efficiency of antigen presentation jointly influence tumor immunogenicity, which largely determines the effectiveness of immune checkpoint blockade (ICB). However, the role of altered antigen processing and presentation machinery (APM) in breast cancer (BRCA) has not been fully elucidated. <h4>Methods:</h4> A series of bioinformatic analyses and machin...

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Literature Corpus work: 48fbe075-888d-58cf-b646-d83b23fd844a
DOI: 10.21203/rs.3.rs-2350621/v1

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