Tumor microenvironment subtypes and immune-related signatures for the prognosis of breast cancer

Abstract excerpt

<title>Abstract</title> <p>To better understand the heterogeneity of tumor microenvironment (TME) and establish a prognostic model for breast cancer in clinical practice, the leukocyte infiltrations of 22 cell types of interest from 2620 breast cancer patients were quantitatively estimated using deconvolution algorithms, and three TME subtypes with distinct molecular and clinical features were identified by unsup...

Topics

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• Breast Neoplasms
• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Gene Ontology
• Gene Regulatory Networks
• Genes, Neoplasm
• Immunophenotyping
• Tumor Microenvironment

Identifiers and source

Literature Corpus work

01e7efc8-7fdb-5aa8-a501-de00bf19f98c

DOI

10.21203/rs.3.rs-53701/v1