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Quantitative profiling of N6-methyladenosine methylome at childhood Ph positive B-cell acute lymphoblastic leukemia reveals a potential mechanism for transcriptional regulation and differential methylation pattern Running title N6-methyladenosine methylome in the childhood Ph positive B-ALL

2022-12-02

Abstract excerpt

<h4>Background: </h4> N6-Methyladenosine (m6A) is the most common methylation modification of messenger RNA (mRNA). Recent researches have revealed potential regulatory functions in various fundamental bioprocesses, suggesting a critical role of m6A in tumorigenesis. Acute lymphoblastic leukemia (ALL) is the most common malignant tumor in children. <h4>Methods: </h4>: The RNA-seq transcriptome data of childhood B...

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Literature Corpus work: 48be3bd8-46b1-5d1d-b5a8-c3c7ab96a856
DOI: 10.21203/rs.3.rs-2321788/v1

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Quantitative profiling of N6-methyladenosine methylome at childhood Ph positive B-cell acute lymphoblastic leukemia reveals a potential mechanism for transcriptional regulation and differential methylation pattern Running title N6-methyladenosine methylome in the childhood Ph positive B-ALLDOI 10.21203/rs.3.rs-2321788/v1Read

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