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The genetic and epigenetic profile of serum S100β in the Lothian Birth Cohort 1936 and its relationship to Alzheimer’s disease

2022-01-27

Abstract excerpt

<h4>Background: </h4> Circulating S100 calcium-binding protein (S100β) is a marker of brain inflammation that has been associated with a range of neurological conditions. To provide insight into the molecular regulation of S100β and its potential causal associations with Alzheimer’s disease, we carried out genome- and epigenome-wide association studies (GWAS/EWAS) of serum S100β levels in older adults and performe...

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Literature Corpus work: 48aa12be-a482-50d1-80fe-0d7a5cff2597
DOI: 10.12688/wellcomeopenres.17322.2

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