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<i>Borrelia burgdorferi bb0164</i> encodes a Na <sup>+</sup> /Ca <sup>2+</sup> antiporter homolog with a novel role in Mn <sup>2+</sup> homeostasis and infectivity

2026-06-17

Abstract excerpt

Borrelia burgdorferi , the Lyme disease causative agent, relies on trace metals for motility, growth, and virulence in the absence of metal transport homologues encoded in the genome. Previous studies characterized borrelial metal transporter ( bmtA ) as a manganese (Mn) transporter and speculated that it is the sole Mn transporter. An oxidative stress transposon library screen identified bb0164 , annotated as a...

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Literature Corpus work
4890ee08-4bcd-5ba9-870c-49a31cb17a02
DOI
10.64898/2026.06.16.732666
Open publication

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