Article
A manganese transporter, BB0219 (BmtA), is required for virulence by the Lyme disease spirochete, Borrelia burgdorferi.
Proceedings of the National Academy of Sciences of the United States of America - 3 Mar 2009
Ouyang Zhiming, He Ming, Oman Tara, Yang X Frank, Norgard Michael V
Abstract excerpt
Borrelia burgdorferi (Bb), the causative agent of Lyme disease, is transmitted to mammalian hosts through an arthropod (tick) vector. To establish infection, Bb must acquire essential nutrients, including transition metals, from its mammalian and tick hosts. Thus far, no metal transporter has been identified in Bb. Here, we report the identification of the first metal transporter, BmtA (BB0219), in Bb....
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