Article

Genomic exploration and in silico prioritization of putative COX-2-targeting metabolites from Streptomyces sp. VITGV156 (MCC 4965)

2026-08-18

Abstract excerpt

Introduction Streptomyces species represent an important source of bioactive natural products, yet systematic genome-guided prioritization of metabolites targeting cyclooxygenase-2 (COX-2/PTGS2) remains limited. This study aimed to investigate the biosynthetic potential of Streptomyces sp. VITGV156 (MCC 4965) using an integrated genome mining and computational drug discovery pipeline. Methods Whole-genome sequenci...

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Literature Corpus work: 48903a33-a0cd-59c2-9977-2dda7cde1017
DOI: 10.3389/fbinf.2026.1840680

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