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Article

Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species.

Nature microbiology - 3 Apr 2017

Nielsen Jens Christian, Grijseels Sietske, Prigent Sylvain, Ji Boyang, Dainat Jacques, Nielsen Kristian Fog, Frisvad Jens Christian, Workman Mhairi, Nielsen Jens

Abstract excerpt

Filamentous fungi produce a wide range of bioactive compounds with important pharmaceutical applications, such as antibiotic penicillins and cholesterol-lowering statins. However, less attention has been paid to fungal secondary metabolites compared to those from bacteria. In this study, we sequenced the genomes of 9 Penicillium species and, together with 15 published genomes, we investigated the secondary...

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PMID: 28368369
DOI: 10.1038/nmicrobiol.2017.44

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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