Article

UV-induced senescence of human dermal fibroblasts restrained by low-stiffness matrix by inhibiting NF-κB activation

2022-08-17

Abstract excerpt

As a hallmark of skin aging, senescent human dermal fibroblasts (HDFs) are known to lose the ability to divide. However, they can still interact with their cellular environment and the surrounding matrix. As the skin ages, the progressive slowing down of HDFs function decreases the skin's structural integrity, which is more serious than if there is the dermal collagen matrix eroded. This leads to matters of the un...

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Identifiers and source

Literature Corpus work: 4852ad3b-7380-586e-a009-a1b060d9538b
DOI: 10.1016/j.engreg.2022.08.002

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