Article

AR(2) eigenvalue modulus as a measure of temporal persistence in gene expression: circadian hierarchy emerges from two coefficients

2026-04-02

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> The mammalian circadian clock organizes gene expression into a hierarchical architecture, but no single quantitative metric has previously captured this hierarchy from expression data alone without biological labels. <bold>Methods:</bold> We apply second-order autoregressive (AR(2)) modeling to gene expression time series and extract the eigenvalue modulus...

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Literature Corpus work: 482f8cfa-8ba2-5eee-98f9-ae988f0a0152
DOI: 10.21203/rs.3.rs-9283100/v1

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