Article
Normalized coefficient of variation (nCV): a method to evaluate circadian clock robustness in population scale data
2021-07-29
Abstract excerpt
<h4>ABSTRACT</h4> Robust oscillation of clock genes is a core feature of the circadian system. Relative amplitude (rAMP) measures the robustness of clock gene oscillations, but only works for longitudinal samples. We lack a method for estimating robust oscillations from human samples without labeled time. We show that the normalized coefficient of variation (nCV) is linearly correlated with rAMP, independent of t...
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Identifiers and source
- Literature Corpus work
- 70641498-a1c7-51c8-aa06-c6155b09a3e5
- DOI
- 10.1101/2021.07.28.454045