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From biogenesis to deep modeling: a holistic review of miRNA-disease prediction computational methods with experimental comparison.

Briefings in bioinformatics - 7 Jan 2026

Xie Siya, Law K L Eddie

Abstract excerpt

Abnormal dysregulation of microRNAs (miRNAs) expression may lead to a wide spectrum of diseases, and as miRNAs play pivotal roles in disease pathogenesis, diagnosis, and therapy, identifying potential miRNA-disease associations (MDAs) is essential for discovering new diagnostic biomarkers, developing targeted therapeutic strategies, and advancing personalized medicine. Traditional wet-lab experiments are...

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PMID: 41554052
DOI: 10.1093/bib/bbaf736
PMCID: PMC12814990

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