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Renal proximal tubule cell state and metabolism are coupled by nuclear receptors

2020-09-21

Abstract excerpt

Kidney disease development is poorly understood due to the complex cellular interactions of more than 25 different cell types, each with specialized functions. Here, we used single cell RNA-sequencing to resolve cell type-specific and cell fraction changes in kidney disease. Whole kidney RNA-sequencing results were strongly influenced by cell fraction changes, but minimally informative to detect cell type-specific...

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Literature Corpus work
47740afb-c473-568c-8903-da3bc47fdfe2
DOI
10.1101/2020.09.21.307231
Open publication

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Renal proximal tubule cell state and metabolism are coupled by nuclear receptorsDOI 10.1101/2020.09.21.307231
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