Article

Comprehensive single cell RNAseq analysis of the kidney reveals novel cell types and unexpected cell plasticity

2017-10-13

Abstract excerpt

A key limitations to understand kidney function and disease development has been that specific cell types responsible for specific homeostatic kidney function or disease phenotypes have not been defined at the molecular level. To fill this gap, we characterized 57,979 cells from healthy mouse kidneys using unbiased single-cell RNA sequencing. We show that genetic mutations that present with similar phenotypes most...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3d45afdc-47e4-5ca6-9b4c-188e1e9d1f58
DOI: 10.1101/203125

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comprehensive single cell RNAseq analysis of the kidney reveals novel cell types and unexpected cell plasticityDOI 10.1101/203125Read

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney diseaseSemantic proximity Read

Single Cell Profiling Reveals Sex, Lineage and Regional Diversity in the Mouse KidneySemantic proximity Read

Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencingSemantic proximity Read

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidneySemantic proximity Read

A cell atlas of the fly kidneySemantic proximity Read

Single-cell analysis of progenitor cell dynamics and lineage specification of the human fetal kidneySemantic proximity Read

An Integrated Atlas of the Human Kidney Spanning Health and DiseasesSemantic proximity Read

Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to InjurySemantic proximity Read

Stepwise developmental mimicry generates proximal-biased kidney organoidsSemantic proximity Read

Urinary single-cell sequencing captures intrarenal injury and repair processes in human acute kidney injurySemantic proximity Read

Novel Human Kidney Cell Subsets Identified by Mux-SeqSemantic proximity Read

Single-cell transcriptomics: a novel precision medicine technique in nephrologySemantic proximity Read