Immune and stromal transcriptional patterns that influence the outcome of classic Hodgkin Lymphoma

Abstract excerpt

<title>Abstract</title> <p>Classic Hodgkin lymphoma (cHL) is characterized by a rich immune microenvironment as the main tumor component. It involves a broad range of cell populations, which are largely unexplored, even though they are known to be essential for growth and survival of Hodgkin and Reed–Sternberg cells. We profiled the gene expression of 25 FFPE cHL samples using NanoString technology and resolved t...

Topics

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• Cancer Genomics and Diagnostics
• Cancer Immunotherapy and Biomarkers
• Gene Expression Profiling
• Hodgkin Disease
• Immune Cell Function and Interaction
• Lymphoma Diagnosis and Treatment
• Mutation
• Tumor Microenvironment

Identifiers and source

Literature Corpus work

47382832-f7ad-58dc-ab9a-109bc18f4af3

DOI

10.21203/rs.3.rs-3067659/v1