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Article

Derivation of Epithelial‐Only Airway Organoids from Human Pluripotent Stem Cells

1 May 2018

Abstract excerpt

New protocols to efficiently generate functional airway epithelial organoids from human pluripotent stem cells (PSCs) would represent a major advance towards effective disease modeling, drug screening and cell based therapies for lung disorders. This unit describes an approach using stage-specific signaling pathway manipulation to differentiate cells to proximal airway epithelium via key developmental...

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PMID: 30040246
DOI: 10.1002/cpsc.51

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