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A Subset of G Protein-Coupled Serotonin Receptor Genes is Linked to a Neuronal Gene Expression Signature and Clinically Favorable Biology in IDH-Mutant Gliomas

2026-08-24

Abstract excerpt

Increasing evidence indicates that neurotransmitter signaling and neuronal interactions are important determinants of glioma biology. However, the clinical and biological significance of serotonin (5-hydroxytryptamine; 5-HT) receptor expression in lower-grade glioma (LGG) remains poorly understood. Here, we investigated G protein-coupled 5-HT receptor genes in LGG using transcriptomic and clinical data from The Ca...

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Literature Corpus work
4669ecc6-f54c-532c-bb91-ed8da006e9ea
DOI
10.64898/2026.08.23.746569
Open publication

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A Subset of G Protein-Coupled Serotonin Receptor Genes is Linked to a Neuronal Gene Expression Signature and Clinically Favorable Biology in IDH-Mutant GliomasDOI 10.64898/2026.08.23.746569
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