Article

<i>DLG2–DLG4</i> Expression is Associated with Improved Survival and a Synaptic Gene Signature in Lower-Grade Glioma

2026-04-15

Abstract excerpt

<h4>Background/Objectives</h4> Increasing evidence indicates that gliomas co-opt mechanisms of excitatory synaptic transmission and plasticity to support tumor progression, yet these processes remain poorly characterized in lower-grade gliomas (LGGs). Here, we investigated whether genes associated with excitatory synaptic function are linked to patient prognosis in LGG. <h4>Methods</h4> A curated panel of 36 syn...

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Literature Corpus work: 87703c15-9b0b-5661-8f30-3b9d35880829
DOI: 10.64898/2026.04.13.718176

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