Article

GUANinE v1.1 Reveals Complementarity of Supervised and Genomic Language Models

2025-12-10

Abstract excerpt

<h4>Background</h4> There has been much debate about the benefits of supervised versus unsupervised learning on genomes. Answering the question of “which is better?” requires the development of comprehensive benchmarks spanning representative functional and evolutionary tasks. Importantly, such benchmarks need large sample sizes to enable well-powered ranking of models under equivalent evaluation, such as L2-regu...

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Literature Corpus work: 4633fbd0-7cdc-5356-8fbc-8dde14d59033
DOI: 10.64898/2025.12.06.692772

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