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Article

Systemic physiological “noise” in fMRI has clinical relevance

2025-08-24

Abstract excerpt

Functional magnetic resonance imaging (fMRI) is central to studying neurobiological mechanisms, yet fMRI has limited clinical utility, highlighting the need for novel approaches. We show that a component of the fMRI signal—the systemic low-frequency oscillation (sLFO), linked to blood flow and physiological measures of arousal—indexes trait- and state-level drug use phenotypes. In individuals who chronically use n...

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Literature Corpus work
461f729e-6022-5ac9-aa5e-93c944e381bc
DOI
10.1101/2025.08.19.25333215
Open publication

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Systemic physiological “noise” in fMRI has clinical relevanceDOI 10.1101/2025.08.19.25333215
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