Article
Using optimal combined moderators to define heterogeneity in neural responses to randomized conditions: Application to the effect of sleep loss on fear learning.
NeuroImage - 1 Nov 2018
Wallace Meredith L, Banihashemi Layla, O'Donnell Christopher, Nimgaonkar Vishwajit L, Kodavali Chowdari, McNamee Rebecca, Germain Anne
Abstract excerpt
Comparing the neural outcomes of two randomized experimental groups is a primary aim of many functional neuroimaging studies. However, between-group effects can be obscured by heterogeneity in neural responses. Optimal Combined Moderator (OCM) approaches have previously been used to clarify heterogeneity in clinical outcomes following treatment randomization. We show that OCMs can also be used to clarify...
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