Article

Two Novel Variants in DYRK1B causative of AOMS3: Expanding the Clinical Spectrum

2020-12-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: We investigated pathogenic <italic>DYRK1B</italic> variants causative of abdominal obesity-metabolic syndrome 3 (AOMS3) in a group of patients originally diagnosed with type 2 diabetes. All <italic>DYRK1B</italic> exons were analyzed in a sample of 509 unrelated adults with type 2 diabetes and 459 controls, all belonging to the DMS1 SIGMA-cohort (ExAC). We perfo...

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Literature Corpus work: 45f89227-134d-5580-8add-157be1ffef3e
DOI: 10.21203/rs.3.rs-133650/v1

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