Article

Analysis of intracellular fatty acid metabolism during Doxorubicin induced senescence of MCF7 cells using Raman Imaging

2025-09-20

Abstract excerpt

<h4>ABSTRACT</h4> Cellular senescence, a stable growth-arrested state induced by stress or chemotherapeutic agents, is accompanied by metabolic remodeling that supports the senescence-associated secretory phenotype (SASP). Among these pathways, lipid and arachidonic acid (AA) metabolism play central roles in maintaining and propagating the senescent state. Here, we used hyperspectral confocal Raman microscopy to...

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Literature Corpus work: 45e118c9-a584-5ed8-8c20-90890b2ed6d0
DOI: 10.1101/2025.09.17.676702

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